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Determination of inhibition constants and IC-50.


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Total downloads: 82
  • Last Updated: Aug 23, 2011
  • License: Shareware N/A
  • OS: Windows XP/2000/98/NT
  • Requirements: No special requirements

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For PlateKi Publisher's description


PlateKi is a Photo & Image software developed by BioKin Ltd. After our trial and test, the software is proved to be official, secure and free. Here is the official description for PlateKi:

PlateKi is Currently used in leading pharmaceutical research laboratories to determine "tight-binding"or "classical" inhibition constants from raw plate-reader data. Associated IC50 values are also determined for compatibility with most corporate databases.


*Automatic model selection in fitting the reaction Progress curves (straight line, quadratic parabola, first or second degree exponential).
*Automatic initial estimate of the inhibition constant.
*Optional robust regression with automatic exclusion of outliers.
*Determination of nonsymmetrical confidence intervals for model parameters according to the profile-t method (Bates & Watts, 1988).
*Fitting of dose-response curves either to the Morrison Equation for tight binding or to the four-parameter Logistic equation.
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