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Genotype error detection and imputation for admixed populations.


Last Week downloads: 0
Total downloads: 86
  • Last Updated: Aug 12, 2011
  • License: Freeware Free
  • OS: Windows XP/2000/98
  • Requirements: No special requirements

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For GEDI-ADMX 1.0.3Publisher's description


GEDI-ADMX is a Photo & Image software developed by Bioinformatics Lab. After our trial and test, the software is proved to be official, secure and free. Here is the official description for GEDI-ADMX:

Edit By BS Editor: Currently GEDI-ADMX handles genotype data from unrelated individuals.

Local ancestry inference uses a Factorial HMMs trained on ancestral haplotypes to impute genotypes at all typed SNP loci (temporarily marking each SNP genotype as missing) under each possible local ancestry.

GEDI-ADMX assigns to each locus the local ancestry that yields the highest imputation accuracy, as assessed using a weighted-voting scheme based on multiple SNP windows centered on the locus of Interest.

Error detection and imputation of missing genotypes at typed SNPs is performed using Multilocus genotype probabilities computed based on the factorial HMM corresponding to the inferred local ancestry.

Imputation of genotypes at each untyped SNP is performed based on posterior genotype probabilities computed using a similar factorial HMM spanning k (Default k=10) typed SNPs before and after the imputed locus.
you can free download GEDI-ADMX 1.0.3 now.


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